Japanese scientists grow functioning testis from mouse stem cells

A team led by University of Osaka researchers has developed a technique to generate testes from mouse embryonic stem cells ...
Quanta Magazine

Break It To Make It: How Fracturing Sculpts Tissues and Organs

Growing tissues can crack, break, and dissociate to form structures that can later withstand immense forces.
eLife

SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven two-cell totipotency transcriptional program in the mouse embryo

Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from ...
The Japan Times

Japanese researchers create mouse testicular organoids in vitro

Two of the researchers were also the first to create ovarian organoids from mouse embryonic stem cells, in 2021.