The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

Nitrous oxide, commonly known as "laughing gas," has been used in anesthesiology practice since the 1800s, but the way it works to create altered states is not well understood. In a study published in ...

Scientists from Scripps Research have shown how anesthetics cause clusters of lipids in the cell membrane to break apart, triggering downstream processes that lead to a loss of consciousness. Share on ...

(A) Schematic diagram of the experimental system that detects calcium release from the endoplasmic reticulum by each ryanodine receptor. (B) Isoflurane selectively activates RyR1 (mean ± standard ...

Mechanical embolectomy performed with general instead of local anesthesia is associated with worse clinical outcomes and poorer survival, according to an article published online March 25, 2014, ahead ...

What's the maximum recommended dose for lidocaine or mepivacaine during dental procedures? The answer remains unclear as guidelines published by dental organizations differ from those of manufacturers ...