While in vivo animal models are commonly employed for pharmacokinetic studies, they are often expensive, low in throughpu,t and typically fail to accurately replicate key characteristics of the human ...
Intestine epithelium-derived exosomes serve as novel mediator in regulating hepatic lipid metabolism
Non-alcoholic fatty liver disease (NAFLD), characterized by excessive hepatic lipid accumulation, poses a high prevalence and can progress to cirrhosis and liver cancer. To enhance preventive and ...
Deep in the folds of the intestine, in microscopic pockets called crypts, a quiet surveillance system is always at work. Stem cells lining the gut wall are not just rebuilding tissue—they are ...
Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...
A study published in the journal Nature, led by Carlene Zindl, Ph.D., and C. Garrett Wilson in the research group of Casey Weaver, M.D., at the University of Alabama at Birmingham, brings new ...
Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in the ...
This story is part of a series exploring human anatomy and physiology complexities. Each story in this collection showcases discoveries reshaping our understanding of the body's inner workings, ...
Nope, this isn’t a small, prickly mammal with a flashy dye job, but a single intestinal epithelial cell. The colorful, hairlike structures are microvilli, which are designed to maximize the cell’s ...
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