Loss of the Y chromosome in aging men is widespread and increasingly linked to serious diseases, challenging assumptions that ...

Human artificial chromosomes (HACs) could be useful tools for both understanding how mammalian chromosomes function and creating synthetic biological systems, but for the last 20 years, they have been ...

AMES, Iowa – A new study led by an Iowa State University scientist sheds light on how organisms have evolved to address imbalances in sex chromosomes. The study looks at a species of softshell turtle, ...

Scientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they ...

Men tend to lose the Y chromosome from their cells as they age. But because the Y bears few genes other than for male determination, it was thought this loss would not affect health. But evidence has ...

For many years, scientists thought they understood the inactivity of X chromosomes in females. However, new University research challenges previous assumptions and could lead to new avenues for ...

Three specific genes on chromosome 21 drive widespread brain changes in Down syndrome, uncovering a new framework for ...

Molecular biologists long thought that domains in the genome's 3D organisation control how genes are expressed. After studying highly rearranged chromosomes in fruit flies, EMBL researchers now reveal ...