A research team has conducted a study exploring the role of the mannose pathway in regulating cell fate decisions in low glucose environments. Their work may hold potential for novel therapeutic ...

A research team has conducted a study exploring the role of the mannose pathway in regulating cell fate decisions in low glucose environments. Their work may hold potential for novel therapeutic ...

A new study has uncovered how an exceptionally scarce protein can orchestrate the assembly of large-scale gene-silencing structures inside cells, and what happens when that process breaks down. The ...

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture. The cohesin complex dynamically restructures ...

The origin of many diseases begins at the cellular level and involves multiple molecular interactions. However, previous methods have struggled to accurately observe changes in individual cells.

A new study published in Nature Biotechnology shows that stem cell differentiation is linked to cellular structures called P-bodies, providing a potential means of controlling cell identity.

Caenorhabditis elegans has long been established as a model organism for investigating the molecular determinants of organogenesis and cell fate specification. Vulval development exemplifies a highly ...

A cell can act in astonishingly complex ways. It must decide for itself whether to grow and multiply, rest, specialise, age or die. This applies just as much to mammalian cells as it does to seemingly ...

Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics of how cells decide their fate. As reported in Nature ...

Shedding light on what determines how cells become what they are meant to be—nerves, bone, muscles, etc.—can also help researchers understand how diseases develop when these biological programs break ...