A mutation in the TDP-43 protein reduces the viability of motor neurons without triggering protein clumps, researchers found.

A research group at the Universidade Federal do Rio de Janeiro has advanced polylaminin, a laminin-based biomaterial, from ...

Figure 1: Axonal transport of Bace, Ps1 and other kinesin-I cargoes is decreased in APP-null mutant mice. The decreased transport of kinesin-I and potential cargoes in APP-null sciatic nerves ...

Perlson and his colleagues now plan to continue studying the mechanisms that drive axonal and NMJ degeneration, while also trying to translate their discoveries into a therapeutic approach.

A physical dimension of a cell is seldom its Achilles' heel. Yet for the neurons that are affected in most kinds of peripheral neuropathy, it is the length of their axons that best accounts for their ...

Diffuse axonal injury (DAI) is a form of traumatic brain injury. It happens when the brain rapidly shifts inside the skull as an injury is occurring. The long connecting fibers in the brain called ...

Absolutely. The electrophysiologic characteristics of neuronopathies and axonopathies depend on how long the condition has been present. In the acute states, there is moderate-to-severe denervation, ...

Axonal's Agentic AI Collaborative Workspace leverages multi-agent technology to shorten the time from insights to actions and streamline commercialization. BOCA RATON, Fla.--(BUSINESS WIRE)--Axonal.AI ...

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS). The study, ...

Diffuse axonal injury (DAI) is a type of traumatic brain injury (TBI). It refers to the shearing of the brain’s long connecting nerve fibers, or axons. DAI can occur during a motor vehicle accident ...